Which of the following is the correct sequenc | vedclass

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(A) In the $Krebs$ cycle,the enzyme $isocitrate$ $dehydrogenase$ catalyzes the oxidation of $isocitric$ $acid$ to $oxalosuccinic$ $acid$ (an unstable

Vedclass · Accepted Answer

Isocitric acid $	o$ Oxalosuccinic acid $	o$ $\alpha$-ketoglutaric acid

Vedclass · Answer

(A) In the $Krebs$ cycle,the enzyme $isocitrate$ $dehydrogenase$ catalyzes the oxidation of $isocitric$ $acid$ to $oxalosuccinic$ $acid$ (an unstable intermediate) in the presence of $NAD^+$. Subsequently,$oxalosuccinic$ $acid$ undergoes $decarboxylation$ to form $\alpha$-ketoglutaric $acid$. Therefore,the correct sequence is: $Isocitric$ $acid$ $	o$ $Oxalosuccinic$ $acid$ $	o$ $\alpha$-ketoglutaric $acid$.

Which of the following is the correct sequence in the $Krebs$ cycle?

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