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(B) The link reaction (also known as the transition reaction or oxidative decarboxylation of pyruvate) connects glycolysis to the Krebs cycle by conve

Vedclass · Accepted Answer

Vitamin $B_1$

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(B) The link reaction (also known as the transition reaction or oxidative decarboxylation of pyruvate) connects glycolysis to the Krebs cycle by converting pyruvic acid into acetyl $CoA$.This reaction is catalyzed by the pyruvate dehydrogenase complex,which requires several cofactors to function,including thiamine pyrophosphate $(TPP)$,which is a derivative of Vitamin $B_1$ (thiamine),as well as $NAD^+$,$CoA$,lipoic acid,and $Mg^{2+}$ ions.Therefore,Vitamin $B_1$ is essential for the catalysis of this reaction.

Which of the following is involved in the catalysis of the link reaction during aerobic respiration?

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