Which of the following observations does $NOT$ provide evidence that the pattern of cleavage is determined by factors in the egg cytoplasm rather than by the genes of the zygote?

• A
  Cleavage is prevented by the injection of a protein synthesis inhibitor.
• B
  Cleavage is not affected by the injection of $RNA$ synthesis inhibitors into the zygote.
• C
  Interspecific hybrid zygotes undergo normal cleavage but die at the beginning of gastrulation.
• D
  The direction of the first cleavage division in the snail $Cepaea$ is determined by the mother's genotype.