Which of the following statements correctly d | vedclass

Name: Exam Paper Generator | JEE NEET Paper Generator | Vedclass
Brand: Vedclass
Rating: 5 (35 reviews)

Question

(B) Aspartic acid is an acidic amino acid with three ionizable groups. The isoelectric point $(pI)$ is the $pH$ at which the molecule exists as a zwit

Vedclass · Accepted Answer

at $pH = 2.95$,aspartic acid shows no net migration towards any electrode

Vedclass · Answer

(B) Aspartic acid is an acidic amino acid with three ionizable groups. The isoelectric point $(pI)$ is the $pH$ at which the molecule exists as a zwitterion with no net charge,resulting in no net migration during electrophoresis. For an acidic amino acid,the $pI$ is calculated using the two lowest $pK_a$ values: $pI = \frac{pK_1 + pK_2}{2} = \frac{2.0 + 3.90}{2} = 2.95$. At $pH = 1.0$ $(pH At $pH = 2.95$ $(pH = pI)$,the molecule has no net charge and shows no net migration. At $pH = 7.0$ and $pH = 9.0$ $(pH > pI)$,the molecule is negatively charged and migrates towards the $(+)$ electrode.

Amino acid	$pH$ at Isoelectric point
$(Amino \ acid)_{I}$	$6$
$(Amino \ acid)_{II}$	$9.8$
$(Amino \ acid)_{III}$	$3.9$

Which of the following statements correctly describes the migration aptitude of aspartic acid during electrophoresis?
$(pK_1 = 2.0, pK_2 = 3.90, pK_3 = 10.0)$
$HOOC-CH_2-CH(NH_2)-COOH$

Similar Questions

How many amino acids are linked together by $(n-1)$ amide bonds?

$HC\equiv CH$ $\xrightarrow[HgSO_4]{H_2SO_4} (A)$ $\xrightarrow[(1) NH_3 + HCN]{(2) H_3O^{\oplus}} (B);$ The product $(B)$ of the given reaction is:

The $pH$ at the isoelectric point of three amino acids are given as follows:

Amino acid $pH$ at Isoelectric point

$(Amino \ acid)_{I}$ $6$

$(Amino \ acid)_{II}$ $9.8$

$(Amino \ acid)_{III}$ $3.9$

$(Amino \ acid)_{II}$ is . . . . . . ?

The number of cyclic tripeptides formed with $2$ amino acids $A$ and $B$ is:

The secondary structure of protein is determined by

Vedclass Test Series

Exam Paper Generator

Online Exam Module

Which of the following statements correctly describes the migration aptitude of aspartic acid during electrophoresis? $(pK_1 = 2.0, pK_2 = 3.90, pK_3 = 10.0)$ $HOOC-CH_2-CH(NH_2)-COOH$