Who among the following is associated with biochemical genetics?

In the $\beta$-globin chain of haemoglobin of an individual,if the sixth amino acid,Glutamic acid (Glu),is replaced by Valine (Val),then the individual will be suffering from:

One way of detecting sex-linked inheritance is:

Select the correct options for the given statements:
Statements:
$X$: Formation of Haemoglobin is controlled by two closely linked genes $HBA1$ and $HBA2$ on chromosome $16$ of each parent.
$Y$: $\beta$-Thalassemia is controlled by a single gene $HBB$ on chromosome $21$ of each parent.

Identify the given pedigree analysis.

If a man who is colour blind marries a woman who is pure normal for colour vision,the chances of their sons having colour blindness is