Who proposed the "Signal Hypothesis" for the | vedclass

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(B) The "Signal Hypothesis" was proposed by $Gunter$ $Blobel$ and $David$ $Sabatini$ in the $1970s$. This hypothesis explains how secretory proteins a

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Blobel and Sabatini

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(B) The "Signal Hypothesis" was proposed by $Gunter$ $Blobel$ and $David$ $Sabatini$ in the $1970s$. This hypothesis explains how secretory proteins are targeted to the endoplasmic reticulum during their synthesis. It states that a specific signal sequence at the $N$-terminus of the nascent polypeptide chain directs the ribosome-mRNA complex to the endoplasmic reticulum membrane.

Who proposed the "Signal Hypothesis" for the biosynthesis of secretory proteins?

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