Which substance,when present in higher amount | vedclass

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(C) Fever,also known as pyrexia,is a systemic response to infection or inflammation. It is primarily triggered by the release of substances known as p

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Production of components like endogenous pyrogens

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(C) Fever,also known as pyrexia,is a systemic response to infection or inflammation. It is primarily triggered by the release of substances known as pyrogens. Endogenous pyrogens are cytokines,such as $Interleukin-1$ $(IL-1)$,$Interleukin-6$ $(IL-6)$,and $Tumor$ $Necrosis$ $Factor$ $(TNF)$,which are released by activated immune cells like macrophages. These substances travel to the hypothalamus in the brain and reset the body's thermostat to a higher temperature,resulting in fever. Therefore,the production of endogenous pyrogens is the direct cause of a fever-like condition.

Which substance,when present in higher amounts in the body,leads to a fever-like condition?

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