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(B) The insertion of a foreign $DNA$ fragment into the coding sequence of an enzyme,such as $\beta$-galactosidase,disrupts the gene's sequence. This p

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Insertional inactivation

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(B) The insertion of a foreign $DNA$ fragment into the coding sequence of an enzyme,such as $\beta$-galactosidase,disrupts the gene's sequence. This process is known as insertional inactivation. Because the gene is interrupted,the functional $\beta$-galactosidase enzyme cannot be synthesized. This technique is commonly used in recombinant $DNA$ technology to screen for recombinant colonies,as non-recombinant colonies will produce the enzyme (turning blue in the presence of a chromogenic substrate),while recombinant colonies will not (appearing white).

What happens if a foreign $DNA$ fragment is inserted into the coding sequence of the $\beta$-galactosidase enzyme in a plasmid containing the coding sequence for the $\beta$-galactosidase enzyme?

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