The first clinical gene therapy was given in $1990$ to a $4$-year-old girl to treat deficiency of:

How many of the following statements are correct?
$(i)$ Mature insulin is made up of $A, B$ and $C$ peptides.
$(ii)$ Removal of $C$-peptide helps in the maturation of insulin.
$(iii)$ In mature insulin,$C$-peptide is present.
$(iv)$ In insulin,chains $A$ and $B$ are linked by disulphide bonds.

Consider the following statements about insulin.
$I.$ Human insulin is made up of $51$ amino acids arranged in two polypeptide chains.
$II.$ The two polypeptide chains are interconnected by two disulphide bridges.
$III.$ In mammals,including humans,insulin is synthesised as a pro-hormone,which contains an extra stretch called the $C$-peptide.
$IV.$ $C$-peptide is not present in the mature insulin.
Which of the statements given above are correct?

Hybridoma cells are .....

Who was the first patient who was given gene therapy? Why was the given treatment recurrent in nature?

Which protein is used for the treatment of emphysema?