The enlargement of the spleen during malaria | vedclass

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(C) During a malaria infection, the $Plasmodium$ parasite infects and destroys red blood cells $(RBCs)$.The spleen is responsible for filtering the bl

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(C) During a malaria infection, the $Plasmodium$ parasite infects and destroys red blood cells $(RBCs)$.The spleen is responsible for filtering the blood and removing damaged or old $RBCs$.Due to the massive destruction of $RBCs$ by the parasite, the spleen has to work excessively to filter out the large volume of dead and damaged $RBCs$.Additionally, the immune system responds by increasing the production of lymphocytes to fight the infection.Therefore, the enlargement of the spleen (splenomegaly) is caused by the accumulation of dead $RBCs$ and the proliferation of immune cells like lymphocytes.

The enlargement of the spleen during malaria is caused by:

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