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Assertion $:-$ The tumor inducing $(Ti)$ plasmid of $Agrobacterium$ $tumefaciens$ has now been modified into a cloning vector.
Reason $:-$ Retroviruses have been disarmed and are now used to deliver genes into animal cells.

Which of the following statements is not true?
$I.$ $DNA$, being a hydrophilic molecule, cannot pass through cell membranes.
$II.$ $Agrobacterium$ $tumefaciens$ delivers a piece of $DNA$ known as $'T-DNA'$ in the $Ti$ plasmid, which transforms normal plant cells into tumour cells to produce chemicals against pathogens.
$III.$ Retrovirus, adenovirus, and papillomavirus are also now used as cloning vectors in animals because of their ability to transform normal cells into cancerous cells.
$IV.$ In genetic engineering, $DNA$ from different sources are cut with the same restriction enzymes so that both $DNA$ fragments have the same kind of sticky ends.
Choose the correct option.

'Cloning' is meant for

Identify '$Q$' and '$R$' in the given figure of a stirred-tank bioreactor.

Match the following columns:
Column-$I$Column-$II$
$(a)$ $Salmonella$$(1)$ $Ti$ plasmid
$(b)$ $E. coli$$(2)$ Thermostable $DNA$ polymerase
$(c)$ $Agrobacterium$ $tumefaciens$$(3)$ Plasmid for first $r-DNA$
$(d)$ $Thermus$ $aquaticus$$(4)$ $EcoR I$

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