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(B) In genetics,the phenotype of an organism is determined by the expression of genes.If a modified allele produces no enzyme at all,the biochemical p

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$(a)$ and $(c)$ are correct

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(B) In genetics,the phenotype of an organism is determined by the expression of genes.If a modified allele produces no enzyme at all,the biochemical pathway is disrupted,leading to a change in the phenotype.Similarly,if the modified allele produces a non-functional enzyme,the substrate cannot be converted into the product,which also alters the phenotype.If the enzyme produced is normal or less efficient,the phenotype may remain unchanged or show only minor variations,but it is not typically considered the primary cause of a significant phenotypic shift compared to the loss of function.Therefore,both $(a)$ and $(c)$ are the conditions where the phenotype is significantly affected due to the loss of enzyme activity.

The phenotype of an individual may be affected if the modified allele produces:
$(a)$ No enzyme at all
$(b)$ The normal/less efficient enzyme
$(c)$ $A$ non-functional enzyme

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The phenotype of an individual may be affected if the modified allele produces:$(a)$ No enzyme at all$(b)$ The normal/less efficient enzyme$(c)$ $A$ non-functional enzyme