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For $n \in N$,in the expansion of $\left(\sqrt[4]{x^{-3}}+a \sqrt[4]{x^5}\right)^n$,the sum of all binomial coefficients lies between $200$ and $400$ and the term independent of $x$ is $448$. Then the value of $a$ is

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If the constant term in the binomial expansion of $\left(\frac{x^{5/2}}{2} - \frac{4}{x^{\ell}}\right)^9$ is $-84$ and the coefficient of $x^{-3\ell}$ is $2^{\alpha}\beta$,where $\beta < 0$ is an odd number,then $|\alpha\ell - \beta|$ is equal to

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