The following pedigree chart shows:

Which of the following genotypes results in hemophilia in females and males respectively?
$\quad\quad$ Female $\quad\quad$ Male

Which disease is caused by a gene defect located on chromosome $16$,leading to a deficiency that affects the transport of respiratory gases?

Haemophilia is a condition where there is . . . . . .

Which one of the following disorders is caused by the substitution of Glutamic acid (Glu) by Valine (Val) at the sixth position of the beta globin chain of the haemoglobin molecule?

The gene for haemophilia is located on the $X$ chromosome. Hence,it is normally impossible for a: